Maximum diastolic potential of human induced pluripotent stem cell-derived cardiomyocytes depends critically on I(Kr).

Maximum diastolic potential of human induced pluripotent stem cell-derived cardiomyocytes depends critically on I(Kr).

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) hold promise for therapeutic applications. To serve these functions, the hiPSC-CM must recapitulate the electrophysiologic properties of native adult cardiomyocytes. This study examines the electrophysiologic characteristics of hi...

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Bibliographic Details
Main Authors: Michael Xavier Doss, José M Di Diego, Robert J Goodrow, Yuesheng Wu, Jonathan M Cordeiro, Vladislav V Nesterenko, Héctor Barajas-Martínez, Dan Hu, Janire Urrutia, Mayurika Desai, Jacqueline A Treat, Agapios Sachinidis, Charles Antzelevitch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3396384?pdf=render

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http://europepmc.org/articles/PMC3396384?pdf=render

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