Polarclean as a Sustainable Reaction Medium for the Waste Minimized Synthesis of Heterocyclic Compounds

Polarclean as a Sustainable Reaction Medium for the Waste Minimized Synthesis of Heterocyclic Compounds

Herein we report the use of Rhodiasolv© Polarclean as a novel polar aprotic solvent for the synthesis of decorated heterocycles via dipolar cycloaddition (isooxazoles) or intramolecular C–H functionalization processes (benzo-fused chromenes). The use of Polarclean allowed to isolate the final produc...

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Bibliographic Details
Main Authors: Francesco Ferlin, Lorenzo Luciani, Orlando Viteritti, Francesco Brunori, Oriana Piermatti, Stefano Santoro, Luigi Vaccaro
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Chemistry
Subjects:
heterocycles
green-synthesis
isoxazoles
triazoles
C–H activation
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2018.00659/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2018.00659/full

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