Neuroinflammation-Induced Upregulation of Glial Cathepsin X Expression and Activity in vivo

Neuroinflammation-Induced Upregulation of Glial Cathepsin X Expression and Activity in vivo

Neuroinflammation is an important factor in the pathogenesis of neurodegenerative diseases. Microglia-derived lysosomal cathepsins have been increasingly recognized as important inflammatory mediators that trigger signaling pathways that aggravate neuroinflammation. In vitro, a contribution to neuro...

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Bibliographic Details
Main Authors: Anja Pišlar, Larisa Tratnjek, Gordana Glavan, Nace Zidar, Marko Živin, Janko Kos
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
neuroinflammation
neurodegeneration
lipopolysaccharide
glia
cathepsin X
neuroprotection
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2020.575453/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2020.575453/full

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