Dissection of the role of PfEMP1 and ICAM-1 in the sensing of Plasmodium-falciparum-infected erythrocytes by natural killer cells.

Dissection of the role of PfEMP1 and ICAM-1 in the sensing of Plasmodium-falciparum-infected erythrocytes by natural killer cells.

BACKGROUND: Host innate immunity contributes to malaria clinical outcome by providing protective inflammatory cytokines such as interferon-gamma, and by shaping the adaptive immune response. Plasmodium falciparum (Pf) is the etiologic agent of the most severe forms of human malaria. Natural Killer (...

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Bibliographic Details
Main Authors: Myriam Baratin, Sophie Roetynck, Bruno Pouvelle, Céline Lemmers, Nicola K Viebig, Sofia Johansson, Philippe Bierling, Artur Scherf, Jürg Gysin, Eric Vivier, Sophie Ugolini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1794133?pdf=render

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http://europepmc.org/articles/PMC1794133?pdf=render

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