Significant impact of circulating tumour DNA mutations on survival in metastatic breast cancer patients

Abstract Mutational analysis of circulating tumour (ct) DNA holds promise as an effective tool to predict the course of metastatic breast cancer (MBC). In the present study we used targeted next generation sequencing of ctDNA to evaluate the impact of cancer driven mutations on the prognosis of MBC....

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Bibliographic Details
Main Authors: Axel Muendlein, Kathrin Geiger, Stella Gaenger, Tobias Dechow, Christoph Nonnenbroich, Andreas Leiherer, Heinz Drexel, Andreas Gaumann, Wolfgang Jagla, Thomas Winder, Frank Mayer, Thomas Decker
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86238-7