Beneficial autoimmunity at body surfaces– immune surveillance and rapid type 2 immunity regulate tissue homeostasis and cancer

Epithelial cells line body surface tissues and provide a physicochemical barrier to the external environment. Frequent microbial and non-microbial challenges such as those imposed by mechanical disruption, injury or exposure to noxious environmental substances including chemicals, carcinogens, ultra...

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Bibliographic Details
Main Authors: Tim eDalessandri, Jessica eStrid
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Immunology
Subjects:
IgE
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00347/full