HLA-DRB1*04 as a Risk Allele to Systemic Lupus Erythematosus and Lupus Nephritis in the Malay Population of Malaysia

HLA-DRB1*04 as a Risk Allele to Systemic Lupus Erythematosus and Lupus Nephritis in the Malay Population of Malaysia

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease afflicting multiple organs. Lupus nephritis (LN) is a serious complication of SLE and remains a major cause of mortality and morbidity. Curative therapy remains unavailable as etiology from genetic and environmental factors is still...

Full description

Bibliographic Details
Main Authors: Malarvili Selvaraja, Voon Kin Chin, Maha Abdullah, Masita Arip, Syafinaz Amin-Nordin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Medicine
Subjects:
systemic lupus erythematosus
lupus nephritis
HLA-DRB1 gene polymorphism
HLA-DRB1*04
Malaysian Malay population
cytokines and free radicals
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2020.598665/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2020.598665/full

Similar Items