Distinguishing mechanisms underlying EMT tristability

Distinguishing mechanisms underlying EMT tristability

Abstract Background The Epithelial-Mesenchymal Transition (EMT) endows epithelial-looking cells with enhanced migratory ability during embryonic development and tissue repair. EMT can also be co-opted by cancer cells to acquire metastatic potential and drug-resistance. Recent research has argued tha...

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Bibliographic Details
Main Authors: Dongya Jia, Mohit Kumar Jolly, Satyendra C. Tripathi, Petra Den Hollander, Bin Huang, Mingyang Lu, Muge Celiktas, Esmeralda Ramirez-Peña, Eshel Ben-Jacob, José N. Onuchic, Samir M. Hanash, Sendurai A. Mani, Herbert Levine
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Cancer Convergence
Subjects:
Epithelial-Mesenchymal transition
EMT
Ternary chimera switch
TCS
Cascading bistable switches
CBS
Online Access:http://link.springer.com/article/10.1186/s41236-017-0005-8

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http://link.springer.com/article/10.1186/s41236-017-0005-8

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