A new interaction between proximal and distal C-terminus of Cav1.2 channels

A new interaction between proximal and distal C-terminus of Cav1.2 channels

Cardiac Cav1.2 channels, coupling membrane stimulation to intracellular Ca2+ signaling, are regulated by multiple cytoplasmic factors, such as calmodulin (CaM), phosphorylation, Ca2+, ATP and intramolecular fragments of the channel. The interaction between distal and proximal C-terminal regulatory d...

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Bibliographic Details
Main Authors: Liting Lyu, Qinghua Gao, Jianjun Xu, Etsuko Minobe, Tong Zhu, Masaki Kameyama
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Journal of Pharmacological Sciences
Subjects:
Cav1.2
Cardiac myocytes
Calmodulin
Patch clamp
Pull-down assay
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861317300403

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http://www.sciencedirect.com/science/article/pii/S1347861317300403

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