Large-scale public data reuse to model immunotherapy response and resistance

Large-scale public data reuse to model immunotherapy response and resistance

Abstract Despite growing numbers of immune checkpoint blockade (ICB) trials with available omics data, it remains challenging to evaluate the robustness of ICB response and immune evasion mechanisms comprehensively. To address these challenges, we integrated large-scale omics data and biomarkers on...

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Bibliographic Details
Main Authors: Jingxin Fu, Karen Li, Wubing Zhang, Changxin Wan, Jing Zhang, Peng Jiang, X. Shirley Liu
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Genome Medicine
Subjects:
Immunotherapy
Immune evasion
Data integration
Web platform
Online Access:http://link.springer.com/article/10.1186/s13073-020-0721-z

Internet

http://link.springer.com/article/10.1186/s13073-020-0721-z

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