Sorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2

Sorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2

The endosome-associated cargo adaptor sorting nexin-27 (SNX27) is linked to various neuropathologies through sorting of integral proteins to the synaptic surface, most notably AMPA receptors. To provide a broader view of SNX27-associated pathologies, we performed proteomics in rat primary neurons to...

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Bibliographic Details
Main Authors: Kirsty J McMillan, Paul J Banks, Francesca LN Hellel, Ruth E Carmichael, Thomas Clairfeuille, Ashley J Evans, Kate J Heesom, Philip Lewis, Brett M Collins, Zafar I Bashir, Jeremy M Henley, Kevin A Wilkinson, Peter J Cullen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
SNX27
membrane trafficking
AMPA receptors
LRFN2
Online Access:https://elifesciences.org/articles/59432

Internet

https://elifesciences.org/articles/59432

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