Low miR-143/miR-145 Cluster Levels Induce Activin A Overexpression in Oral Squamous Cell Carcinomas, Which Contributes to Poor Prognosis.

Low miR-143/miR-145 Cluster Levels Induce Activin A Overexpression in Oral Squamous Cell Carcinomas, Which Contributes to Poor Prognosis.

Deregulated expression of activin A is reported in several tumors, but its biological functions in oral squamous cell carcinoma (OSCC) are unknown. Here, we investigate whether activin A can play a causal role in OSCCs. Activin A expression was assessed by qPCR and immunohistochemistry in OSCC tissu...

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Bibliographic Details
Main Authors: Andreia Bufalino, Nilva K Cervigne, Carine Ervolino de Oliveira, Felipe Paiva Fonseca, Priscila Campioni Rodrigues, Carolina Carneiro Soares Macedo, Lays Martin Sobral, Marcia Costa Miguel, Marcio Ajudarte Lopes, Adriana Franco Paes Leme, Daniel W Lambert, Tuula A Salo, Luiz Paulo Kowalski, Edgard Graner, Ricardo D Coletta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4552554?pdf=render

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http://europepmc.org/articles/PMC4552554?pdf=render

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