Immunogenicity and protective efficacy of prime-boost immunization in mice vaccinated with live and inactivated influenza A (H5N1) vaccines

Avian influenza A (H1N1) in humans is characterized by severe clinical manifestation and high mortality. The main drawback of current human H5N1 vaccines is related to low immunogenicity. Prime-boost vaccination is considered as an effective approach to enhance vaccine immunogenicity. The aim of thi...

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Bibliographic Details
Main Authors: I. Losev, G. Petukhova, I. Isakova-Sivak, L. Rudenko
Format: Article
Language:Russian
Published: Sankt-Peterburg : NIIÈM imeni Pastera 2019-05-01
Series:Infekciâ i Immunitet
Subjects:
Online Access:https://www.iimmun.ru/iimm/article/view/618