Urinary K+ promotes irritative voiding symptoms and pain in the face of urothelial barrier dysfunction

Abstract The internal surface of the bladder is lined by the urothelium, a stratified epithelium that forms an impermeable barrier to water and urine constituents. Abnormalities in the urothelial barrier have been described in certain forms of cystitis and were hypothesized to contribute to irritati...

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Bibliographic Details
Main Authors: Nicolas Montalbetti, Sean D. Stocker, Gerard Apodaca, Sheldon I. Bastacky, Marcelo D. Carattino
Format: Article
Language:English
Published: Nature Publishing Group 2019-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-41971-y