Mitochondrial DNA content of peripheral blood mononuclear cells in ART untreated & stavudine/zidovudine treated HIV-1-infected patients

Mitochondrial DNA content of peripheral blood mononuclear cells in ART untreated & stavudine/zidovudine treated HIV-1-infected patients

Background & objectives: Nucleoside reverse transcriptase inhibitors (NRTIs) are known to cause mitochondrial toxicity. This study was done to estimate mitochondrial DNA (mtDNA) content of peripheral blood mononuclear cells (PBMCs) among human immunodeficiency virus (HIV) infected, NRTI treated...

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Bibliographic Details
Main Authors: Dhakshinamoorthy Subashini, Thongadi Ramesh Dinesha, Rao B Srirama, Jayaseelan Boobalan, Selvamuthu Poongulali, Devaraj A Chitra, Sarvode N Mothi, Sunil Suhas Solomon, Shanmugam Saravanan, Suniti Solomon, Pachamuthu Balakrishnan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Indian Journal of Medical Research
Subjects:
ART naïve - HIV - mitochondrial dysfunction - mitochondrial DNA - nucleoside reverse transcriptase inhibitors - peripheral blood mononuclear cells - toxicity
Online Access:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2018;volume=148;issue=2;spage=207;epage=214;aulast=Subashini

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http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2018;volume=148;issue=2;spage=207;epage=214;aulast=Subashini

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