Learning protein constitutive motifs from sequence data
Statistical analysis of evolutionary-related protein sequences provides information about their structure, function, and history. We show that Restricted Boltzmann Machines (RBM), designed to learn complex high-dimensional data and their statistical features, can efficiently model protein families f...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-03-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/39397 |