Human microRNA oncogenes and tumor suppressors show significantly different biological patterns: from functions to targets.

MicroRNAs (miRNAs) are small noncoding RNAs which play essential roles in many important biological processes. Therefore, their dysfunction is associated with a variety of human diseases, including cancer. Increasing evidence shows that miRNAs can act as oncogenes or tumor suppressors, and although...

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Bibliographic Details
Main Authors: Dong Wang, Chengxiang Qiu, Haijun Zhang, Juan Wang, Qinghua Cui, Yuxin Yin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2948010?pdf=render