Acute MPTP Treatment Impairs Dendritic Spine Density in the Mouse Hippocampus

Among the animal models of Parkinson’s disease (PD), the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned mouse model has shown both dopaminergic (DA) damage and related motor control defects, as observed in patients with PD. Recent studies have suggested that the DA system interacts wit...

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Bibliographic Details
Main Authors: Poornima D. E. Weerasinghe-Mudiyanselage, Mary Jasmin Ang, Mai Wada, Sung-Ho Kim, Taekyun Shin, Miyoung Yang, Changjong Moon
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/11/7/833