CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17

Abstract Background Metastasis causes the vast majority of colorectal carcinoma (CRC)-related deaths. However, little is known about the specific traits and underlying mechanisms of metastasis-initiating cells in primary CRC. And whether or not circular RNAs (circRNAs) take part in this particular e...

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Bibliographic Details
Main Authors: Kai Han, Feng-Wei Wang, Chen-Hui Cao, Han Ling, Jie-Wei Chen, Ri-Xin Chen, Zi-Hao Feng, Jie Luo, Xiao-Han Jin, Jin-Ling Duan, Shu-Man Li, Ning-Fang Ma, Jing-Ping Yun, Xin-Yuan Guan, Zhi-Zhong Pan, Ping Lan, Rui-Hua Xu, Dan Xie
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Molecular Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12943-020-01184-8