Early Induction of Human Regulatory Dermal Antigen Presenting Cells by Skin-Penetrating Schistosoma Mansoni Cercariae

Following initial invasion of Schistosoma mansoni cercariae, schistosomula reside in the skin for several days during which they can interact with the dermal immune system. While murine experiments have indicated that exposure to radiation-attenuated (RA) cercariae can generate protective immunity w...

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Bibliographic Details
Main Authors: Béatrice M. F. Winkel, Mirjam R. Dalenberg, Clarize M. de Korne, Carola Feijt, Marijke C. C. Langenberg, Leonard Pelgrom, Munisha S. Ganesh, Maria Yazdanbakhsh, Hermelijn Helene Smits, Esther C. de Jong, Bart Everts, Fijs W. B. van Leeuwen, Cornelis H. Hokke, Meta Roestenberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02510/full