Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex

Fe/S clusters are synthesized by the mitochondrial iron-sulfur cluster assembly (ISC) machinery. Here the authors combine crystallography and small angle X-ray scattering measurements to structurally characterize the core ISC complex and give functional insights into eukaryotic Fe/S cluster synthesi...

Full description

Bibliographic Details
Main Authors: Michal T. Boniecki, Sven A. Freibert, Ulrich Mühlenhoff, Roland Lill, Miroslaw Cygler
Format: Article
Language:English
Published: Nature Publishing Group 2017-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01497-1