BRAF V600E mutational load as a prognosis biomarker in malignant melanoma.

Analyzing the mutational load of driver mutations in melanoma could provide valuable information regarding its progression. We aimed at analyzing the heterogeneity of mutational load of BRAF V600E in biopsies of melanoma patients of different stages, and investigating its potential as a prognosis fa...

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Bibliographic Details
Main Authors: Arrate Sevilla, M Celia Morales, Pilar A Ezkurra, Javier Rasero, Verónica Velasco, Goikoane Cancho-Galan, Ana Sánchez-Diez, Karmele Mujika, Cristina Penas, Isabel Smith, Aintzane Asumendi, Jesús M Cortés, Maria Dolores Boyano, Santos Alonso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0230136