Distinct shed microvesicle and exosome microRNA signatures reveal diagnostic markers for colorectal cancer.

Extracellular vesicle (EV) microRNAs are of major interest as potential diagnostic biomarkers in all cancer types. This study aims to identify miRNA profiles of shed microvesicles (sMVs) and exosomes (Exos) secreted from the isogenic colorectal cancer (CRC) cell lines SW480 and SW620 and evaluate th...

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Bibliographic Details
Main Authors: Maoshan Chen, Rong Xu, Alin Rai, Wittaya Suwakulsiri, Keiichi Izumikawa, Hideaki Ishikawa, David W Greening, Nobuhiro Takahashi, Richard J Simpson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0210003