Three-dimensional (3D) evaluation of liquid distribution in shake flask using an optical fluorescence technique

Abstract Background Biotechnological development in shake flask necessitates vital engineering parameters e.g. volumetric power input, mixing time, gas liquid mass transfer coefficient, hydromechanical stress and effective shear rate. Determination and optimization of these parameters through experi...

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Bibliographic Details
Main Authors: Amizon Azizan, Jochen Büchs
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Journal of Biological Engineering
Subjects:
CFD
Online Access:http://link.springer.com/article/10.1186/s13036-017-0070-7