G-Protein-Coupled Estrogen Receptor (GPER)-Specific Agonist G1 Induces ER Stress Leading to Cell Death in MCF-7 Cells
The G-protein-coupled estrogen receptor (GPER) mediates rapid non-genomic effects of estrogen. Although GPER is able to induce proliferation, it is down-regulated in breast, ovarian and colorectal cancer. During cancer progression, high expression levels of GPER are favorable for patients’...
Main Authors: | Diep-Khanh Ho Vo, Roland Hartig, Sönke Weinert, Johannes Haybaeck, Norbert Nass |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-09-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/9/9/503 |
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