Induction of Apurinic Endonuclease 1 Overexpression by Endoplasmic Reticulum Stress in Hepatoma Cells

Induction of Apurinic Endonuclease 1 Overexpression by Endoplasmic Reticulum Stress in Hepatoma Cells

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide with poor prognosis due to resistance to conventional chemotherapy and limited efficacy of radiotherapy. Previous studies have noted the induction of endoplasmic reticulum stress or apurinic endonuclease 1 (APE1) express...

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Bibliographic Details
Main Authors: Tsung-Lin Cheng, Pin-Shern Chen, Ren-Hao Li, Shyng-Shiou Yuan, Ih-Jen Su, Jui-Hsiang Hung
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:International Journal of Molecular Sciences
Subjects:
hepatocellular carcinoma
Huh-7
HepG2
NeHepLxHT
hepatitis B virus
hepatitis B virus pre-S2∆ large mutant surface protein
endoplasmic reticulum stress
apurinic endonuclease 1
GRP78
Online Access:http://www.mdpi.com/1422-0067/15/7/12442

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http://www.mdpi.com/1422-0067/15/7/12442

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