Tetrahydrobiopterin Protects against Radiation-induced Growth Inhibition in H9c2 Cardiomyocytes

Tetrahydrobiopterin Protects against Radiation-induced Growth Inhibition in H9c2 Cardiomyocytes

Background: Tetrahydrobiopterin (BH4) is an essential cofactor of nitric oxide synthases (NOSs) for the synthesis of nitric oxide (NO). BH4 therapy can reverse the disease-related redox disequilibrium observed with BH4 deficiency. However, whether BH4 exerts a protective effect against radiation-ind...

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Bibliographic Details
Main Authors: Zheng-Yi Zhang, Yi Li, Rui Li, An-An Zhang, Bo Shang, Jing Yu, Xiao-Dong Xie
Format: Article
Language:English
Published: Wolters Kluwer 2016-01-01
Series:Chinese Medical Journal
Subjects:
Endothelial Nitric Oxide Synthase; Oxidative Stress; Proliferation; Radiation-induced Heart Disease; Tetrahydrobiopterin
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=22;spage=2733;epage=2740;aulast=Zhang

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http://www.cmj.org/article.asp?issn=0366-6999;year=2016;volume=129;issue=22;spage=2733;epage=2740;aulast=Zhang

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