Enhancing β-Carotene Production in Escherichia coli by Perturbing Central Carbon Metabolism and Improving the NADPH Supply

Enhancing β-Carotene Production in Escherichia coli by Perturbing Central Carbon Metabolism and Improving the NADPH Supply

Beta (β)-carotene (C40H56; a provitamin) is a particularly important carotenoid for human health. Many studies have focused on engineering Escherichia coli as an efficient heterologous producer of β-carotene. Moreover, several strains with potential for use in the industrial production of this provi...

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Bibliographic Details
Main Authors: Yuanqing Wu, Panpan Yan, Yang Li, Xuewei Liu, Zhiwen Wang, Tao Chen, Xueming Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Escherichia coli
metabolic engineering
β-carotene
phosphotransferase system inactivation
NADPH supply
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00585/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00585/full

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