Folliculin contributes to VHL tumor suppressing activity in renal cancer through regulation of autophagy.

Folliculin contributes to VHL tumor suppressing activity in renal cancer through regulation of autophagy.

Von Hippel-Lindau tumor suppressor (VHL) is lost in the majority of clear cell renal cell carcinomas (ccRCC). Folliculin (FLCN) is a tumor suppressor whose function is lost in Birt-Hogg-Dubé syndrome (BHD), a disorder characterized by renal cancer of multiple histological types including clear cell...

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Bibliographic Details
Main Authors: Prabhat Bastola, Yiwen Stratton, Emily Kellner, Olga Mikhaylova, Ying Yi, Maureen A Sartor, Mario Medvedovic, Jacek Biesiada, Jarek Meller, Maria F Czyzyk-Krzeska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3726479?pdf=render

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http://europepmc.org/articles/PMC3726479?pdf=render

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