Characterization of neuronal populations in the human trigeminal ganglion and their association with latent herpes simplex virus-1 infection.

Following primary infection Herpes simplex virus-1 (HSV-1) establishes lifelong latency in the neurons of human sensory ganglia. Upon reactivation HSV-1 can cause neurological diseases such as facial palsy, vestibular neuritis or encephalitis. Certain populations of sensory neurons have been shown t...

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Bibliographic Details
Main Authors: Sarah E Flowerdew, Desiree Wick, Susanne Himmelein, Anja K E Horn, Inga Sinicina, Michael Strupp, Thomas Brandt, Diethilde Theil, Katharina Hüfner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3868591?pdf=render