Recombinase-Dependent Mouse Lines for Chemogenetic Activation of Genetically Defined Cell Types

Recombinase-Dependent Mouse Lines for Chemogenetic Activation of Genetically Defined Cell Types

Chemogenetic technologies, including the mutated human Gq-coupled M3 muscarinic receptor (hM3Dq), have greatly facilitated our ability to directly link changes in cellular activity to altered physiology and behavior. Here, we extend the hM3Dq toolkit with recombinase-responsive mouse lines that perm...

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Bibliographic Details
Main Authors: Natale R. Sciolino, Nicholas W. Plummer, Yu-Wei Chen, Georgia M. Alexander, Sabrina D. Robertson, Serena M. Dudek, Zoe A. McElligott, Patricia Jensen
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716306179

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http://www.sciencedirect.com/science/article/pii/S2211124716306179

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