Membrane binding controls ordered self-assembly of animal septins

Septins are conserved cytoskeletal proteins that regulate cell cortex mechanics. The mechanisms of their interactions with the plasma membrane remain poorly understood. Here, we show by cell-free reconstitution that binding to flat lipid membranes requires electrostatic interactions of septins with...

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Bibliographic Details
Main Authors: Agata Szuba, Fouzia Bano, Gerard Castro-Linares, Francois Iv, Manos Mavrakis, Ralf P Richter, Aurélie Bertin, Gijsje H Koenderink
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/63349