cAMP-Epac Pathway Stimulation Modulate Connexin-43 and MicroRNA-21 Expression in Glioma Cells

Introduction: Malignant astrocytic gliomas are the most common and lethal brain malignancies due to their refractory to the current therapies. Nowadays, molecular targeted therapy has attracted great attention in treatment of glioma. Connexin 43 (Cx43) and micro ribonucleic acid- 21(miR-21) are amon...

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Main Authors: Hossein Mostafavi, Mojtaba Khaksarian, Mohammad Taghi Joghataei, Sadegh Yoosefee, Mahmoud Reza Hadjighassem, Maryam Soleimannejad, Raheleh Gholamzadeh, Sanam Seifollahi Bahnamiri
Format: Article
Language:English
Published: Iran University of Medical Sciences 2015-02-01
Series:Basic and Clinical Neuroscience
Subjects:
Online Access:http://bcn.iums.ac.ir/browse.php?a_code=A-10-606-1&slc_lang=en&sid=1