The Serine Protease HTRA-1 Is a Biomarker for ROP and Mediates Retinal Neovascularization

The Serine Protease HTRA-1 Is a Biomarker for ROP and Mediates Retinal Neovascularization

Retinopathy of prematurity (ROP) is a blinding aberrancy of retinal vascular maturation in preterm infants. Despite delayed onset after preterm birth, representing a window for therapeutic intervention, we cannot prevent or cure ROP blindness. A natural form of ROP protection exists in the setting o...

Full description

Bibliographic Details
Main Authors: Leah A. Owen, Kinsey Shirer, Samuel A. Collazo, Kathryn Szczotka, Shawna Baker, Blair Wood, Lara Carroll, Benjamin Haaland, Takeshi Iwata, Lakshmi D. Katikaneni, Margaret M. DeAngelis
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
retinopathy of prematurity
biomarker
systems biology
preeclampsia
HTRA-1
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2020.605918/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2020.605918/full

Similar Items