Combined Ubisol-Q<sub>10</sub> and Ashwagandha Root Extract Target Multiple Biochemical Mechanisms and Reduces Neurodegeneration in a Paraquat-Induced Rat Model of Parkinson’s Disease

Combined Ubisol-Q<sub>10</sub> and Ashwagandha Root Extract Target Multiple Biochemical Mechanisms and Reduces Neurodegeneration in a Paraquat-Induced Rat Model of Parkinson’s Disease

Parkinson’s disease (PD) is characterized by progressive neurodegeneration in the substantia nigra (SN) region resulting in loss of movement coordination. Current therapies only provide symptomatic relief, and there is no agent to halt the progression of PD. Previously, Ubisol-Q<sub>10</sub...

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Bibliographic Details
Main Authors: Caleb Vegh, Darcy Wear, Iva Okaj, Rachel Huggard, Lauren Culmone, Sezen Eren, Jerome Cohen, Arun K. Rishi, Siyaram Pandey
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Antioxidants
Subjects:
Parkinson’s disease
oxidative stress
autophagy
neuroinflammation
paraquat
mitochondrial dysfunction
Online Access:https://www.mdpi.com/2076-3921/10/4/563

Internet

https://www.mdpi.com/2076-3921/10/4/563

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