Progranulin signaling in sepsis, community-acquired bacterial pneumonia and COVID-19: a comparative, observational study

Progranulin signaling in sepsis, community-acquired bacterial pneumonia and COVID-19: a comparative, observational study

Abstract Background Progranulin is a widely expressed pleiotropic growth factor with a central regulatory effect during the early immune response in sepsis. Progranulin signaling has not been systematically studied and compared between sepsis, community-acquired pneumonia (CAP), COVID-19 pneumonia a...

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Main Authors: Florian Brandes, Melanie Borrmann, Dominik Buschmann, Agnes S. Meidert, Marlene Reithmair, Markus Langkamp, Lutz Pridzun, Benedikt Kirchner, Jean-Noël Billaud, Nirav M. Amin, Joseph C. Pearson, Matthias Klein, Daniela Hauer, Clarissa Gevargez Zoubalan, Anja Lindemann, Alexander Choukér, Thomas W. Felbinger, Ortrud K. Steinlein, Michael W. Pfaffl, Ines Kaufmann, Gustav Schelling
Format: Article
Language:English
Published: SpringerOpen 2021-09-01
Series:Intensive Care Medicine Experimental
Subjects:
Sepsis
Pneumonia
COVID-19
Progranulin
Procalcitonin
Sensitivity
Online Access:https://doi.org/10.1186/s40635-021-00406-7

Internet

https://doi.org/10.1186/s40635-021-00406-7

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