Are NSAIDs useful to treat Alzheimer's disease or mild cognitive impairment?

Several epidemiological studies suggest that long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) may protect subjects carrying one or more ε4 allele of the apolipoprotein E (APOE ε4) against the onset of Alzheimer’s disease (AD). The biological mechanism...

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Bibliographic Details
Main Authors: Bruno P Imbimbo, Vincenzo Solfrizzi, Francesco Panza
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2010.00019/full