Critical Roles of the PI3K-Akt-mTOR Signaling Pathway in Apoptosis and Autophagy of Astrocytes Induced by Methamphetamine

Critical Roles of the PI3K-Akt-mTOR Signaling Pathway in Apoptosis and Autophagy of Astrocytes Induced by Methamphetamine

This study aimed to reveal potential roles of the phosphatidylinositol 3 kinase (PI3K)-protein kinase B (Akt)-mammalian target of rapamycin (mTOR) signaling pathway in apoptosis and autophagy of astrocytes induced by methamphetamine (METH). A Cell Counting Kit-8 (CCK-8) was used to determine the red...

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Bibliographic Details
Main Authors: Liu Han-Qing, An Ya-Wen, Hu A-Zhen, Li Ming-Hua, Wu Jue-Lian, Liu Li, Shi Yu, Cui Guang-Hui, Chen Yun
Format: Article
Language:English
Published: De Gruyter 2019-02-01
Series:Open Chemistry
Subjects:
methamphetamine
protein kinase b
astrocyte
apoptosis
autophagy
Online Access:https://doi.org/10.1515/chem-2019-0015

Internet

https://doi.org/10.1515/chem-2019-0015

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