Fibroblast growth factor-5 promotes spermatogonial stem cell proliferation via ERK and AKT activation

Fibroblast growth factor-5 promotes spermatogonial stem cell proliferation via ERK and AKT activation

Abstract Background Sertoli cells are the most important somatic cells contributing to the microenvironment (named niche) for spermatogonial stem cells (SSCs). They produce amounts of crucial growth factors and structure proteins that play essential roles in the complex processes of male SSCs surviv...

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Bibliographic Details
Main Authors: Ruhui Tian, Chencheng Yao, Chao Yang, Zijue Zhu, Chong Li, Erlei Zhi, Junlong Wang, Peng Li, Huixing Chen, Qingqing Yuan, Zuping He, Zheng Li
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Stem Cell Research & Therapy
Online Access:http://link.springer.com/article/10.1186/s13287-019-1139-7

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http://link.springer.com/article/10.1186/s13287-019-1139-7

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