Tandem riboswitches form a natural Boolean logic gate to control purine metabolism in bacteria

Gene control systems sometimes interpret multiple signals to set the expression levels of the genes they regulate. In rare instances, ligand-binding riboswitch aptamers form tandem arrangements to approximate the function of specific two-input Boolean logic gates. Here, we report the discovery of ri...

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Bibliographic Details
Main Authors: Madeline E Sherlock, Narasimhan Sudarsan, Shira Stav, Ronald R Breaker
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/33908