The Innate Immune Response to Infection Induces Erythropoietin-Dependent Replenishment of the Dendritic Cell Compartment

The Innate Immune Response to Infection Induces Erythropoietin-Dependent Replenishment of the Dendritic Cell Compartment

Dendritic cells (DC) play a key role in the adaptive immune response due to their ability to present antigens and stimulate naïve T cells. Many bacteria and viruses can efficiently target DC, resulting in impairment of their immunostimulatory function or elimination. Hence, the DC compartment requir...

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Bibliographic Details
Main Authors: Henrik Einwächter, Alexander Heiseke, Andreas Schlitzer, Georg Gasteiger, Heiko Adler, David Voehringer, Markus G. Manz, Zsolt Ruzsics, Lars Dölken, Ulrich H. Koszinowski, Tim Sparwasser, Wolfgang Reindl, Stefan Jordan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
infection
inflammation
erythropoietin
dendritic cell
extramedullary hematopoiesis
TER119
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01627/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01627/full

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