Prion strains associated with iatrogenic CJD in French and UK human growth hormone recipients

Prion strains associated with iatrogenic CJD in French and UK human growth hormone recipients

Abstract Treatment with human pituitary-derived growth hormone (hGH) was responsible for a significant proportion of iatrogenic Creutzfeldt–Jakob disease (iCJD) cases. France and the UK experienced the largest case numbers of hGH-iCJD, with 122 and 81 cases respectively. Differences in the frequency...

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Bibliographic Details
Main Authors: Jean-Yves Douet, Alvina Huor, Hervé Cassard, Séverine Lugan, Naïma Aron, Chloé Mesic, Didier Vilette, Tomás Barrio, Nathalie Streichenberger, Armand Perret-Liaudet, Marie-Bernadette Delisle, Patrice Péran, Jean-Philippe Deslys, Emmanuel Comoy, Jean-Luc Vilotte, Katayoun Goudarzi, Vincent Béringue, Marcelo A. Barria, Diane L. Ritchie, James W. Ironside, Olivier Andréoletti
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Acta Neuropathologica Communications
Subjects:
Prion disease
Iatrogenic CJD
Growth hormone
Online Access:https://doi.org/10.1186/s40478-021-01247-x

Internet

https://doi.org/10.1186/s40478-021-01247-x

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