Exosomal ERp44 derived from ER-stressed cells strengthens cisplatin resistance of nasopharyngeal carcinoma

Exosomal ERp44 derived from ER-stressed cells strengthens cisplatin resistance of nasopharyngeal carcinoma

Abstract Background Nasopharyngeal carcinoma (NPC) is one of the most common malignancies in head and neck. Platinum-based chemotherapy is an important treatment for NPC. However, the molecular mechanism of resistance to platinum drug remains unknown. Endoplasmic reticulum resident protein 44(ERp44)...

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Bibliographic Details
Main Authors: Tian Xia, Hui Tian, Kaiwen Zhang, Siyu Zhang, Wenhui Chen, Si Shi, Yiwen You
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Cancer
Subjects:
Nasopharyngeal carcinoma
ERp44
ER stress
Exosomes
Chemoresistance
Online Access:https://doi.org/10.1186/s12885-021-08712-9

Internet

https://doi.org/10.1186/s12885-021-08712-9

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