Vitamin B1 Helps to Limit Mycobacterium tuberculosis Growth via Regulating Innate Immunity in a Peroxisome Proliferator-Activated Receptor-γ-Dependent Manner

Vitamin B1 Helps to Limit Mycobacterium tuberculosis Growth via Regulating Innate Immunity in a Peroxisome Proliferator-Activated Receptor-γ-Dependent Manner

It is known that vitamin B1 (VB1) has a protective effect against oxidative retinal damage induced by anti-tuberculosis drugs. However, it remains unclear whether VB1 regulates immune responses during Mycobacterium tuberculosis (MTB) infection. We report here that VB1 promotes the protective immune...

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Bibliographic Details
Main Authors: Shengfeng Hu, Wenting He, Xialin Du, Yulan Huang, Yuling Fu, Yalong Yang, Chuxuan Hu, Silin Li, Qinshu Wang, Qian Wen, Xinying Zhou, Chaoying Zhou, Xiao-Ping Zhong, Li Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
Subjects:
Mycobacterium tuberculosis
vitamin B1
macrophages
peroxisome proliferator-activated receptor-γ
adjuvant
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01778/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.01778/full

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