Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors

Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors

<p>Abstract</p> <p>The zinc-dependent mammalian histone deacetylase (HDAC) family comprises 11 enzymes, which have specific and critical functions in development and tissue homeostasis. Mounting evidence points to a link between misregulated HDAC activity and many oncologic and non...

Full description

Bibliographic Details
Main Authors: Delcuve Geneviève P, Khan Dilshad H, Davie James R
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Clinical Epigenetics
Subjects:
histone deacetylase
HDAC
HDAC inhibitors
HDAC complexes
gene expression
noncoding RNAs
epigenetics
Online Access:http://www.clinicalepigeneticsjournal.com/content/4/1/5

Internet

http://www.clinicalepigeneticsjournal.com/content/4/1/5

Similar Items