Integrating phosphorylation network with transcriptional network reveals novel functional relationships.

Phosphorylation and transcriptional regulation events are critical for cells to transmit and respond to signals. In spite of its importance, systems-level strategies that couple these two networks have yet to be presented. Here we introduce a novel approach that integrates the physical and functiona...

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Bibliographic Details
Main Authors: Lin Wang, Lin Hou, Minping Qian, Minghua Deng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3303811?pdf=render