Development and validation of SPE-HPLC method for the determination of carbamazepine and its metabolites carbamazepine epoxide and carbamazepine trans-diol in plasma

Development and validation of SPE-HPLC method for the determination of carbamazepine and its metabolites carbamazepine epoxide and carbamazepine trans-diol in plasma

SPE-HPLC method has been developed and validated for rapid analysis of carbamazepine and its two metabolites carbamazepine epoxide and carbamazepine trans-diol in human plasma. The analysis was performed using C18 Bakerbond-BDC analytical column (250 mm x 4.6 mm i.d., particle size 5 μm). The op...

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Bibliographic Details
Main Authors: Spasić Mirjana, Lukić Stevo, Živanović Slavoljub, Ivanović Ivana, Veličković-Radovanović Radmila, Živanović Ljiljana, Protić Ana, Džodić Predrag
Format: Article
Language:English
Published: Serbian Chemical Society 2012-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
human plasma
carbamazepine
carbamazepine epoxide
carbamazepine trans-diol
solid phase extraction.
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2012/0352-51391200084D.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0352-5139/2012/0352-51391200084D.pdf

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