Production of recombinant AAV vectors encoding insulin-like growth factor I is enhanced by interaction among AAV <it>rep </it>regulatory sequences

<p>Abstract</p> <p>Background</p> <p>Adeno-associated virus (AAV) vectors are promising tools for gene therapy. Currently, their potential is limited by difficulties in producing high vector yields with which to generate transgene protein product. AAV vector production...

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Bibliographic Details
Main Authors: Dilley Robert, Mercer Scott A, Shi Shuiliang, Trippel Stephen B
Format: Article
Language:English
Published: BMC 2009-01-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/6/1/3