Inhibition of p38-MAPK signaling pathway attenuates breast cancer induced bone pain and disease progression in a murine model of cancer-induced bone pain

Inhibition of p38-MAPK signaling pathway attenuates breast cancer induced bone pain and disease progression in a murine model of cancer-induced bone pain

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<p>Abstract</p> <p>Background</p> <p>Mechanisms driving cancer-induced bone pain are poorly understood. A central factor implicated to be a key player in the process of tumorigenesis, osteoclastogenesis and nociception is p38 MAPK. We determined the role of p38 MAPK in...

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Bibliographic Details
Main Authors: Vanderah Todd W, Nelson Mark A, Chandramouli Anupama, Okun Alec, Sukhtankar Devki, Cress Anne E, Porreca Frank, King Tamara
Format: Article
Language:English
Published: SAGE Publishing 2011-10-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/7/1/81

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http://www.molecularpain.com/content/7/1/81

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