Clinical and Laboratory Associations with Methotrexate Metabolism Gene Polymorphisms in Rheumatoid Arthritis

Clinical and Laboratory Associations with Methotrexate Metabolism Gene Polymorphisms in Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that causes loss of joint function and significantly reduces quality of life. Plasma metabolite concentrations of disease-modifying anti-rheumatic drugs (DMARDs) can influence treatment efficacy and toxicity. This study explored the...

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Bibliographic Details
Main Authors: Leon G. D’Cruz, Kevin G. McEleney, Kyle B. C. Tan, Priyank Shukla, Philip V. Gardiner, Patricia Connolly, Caroline Conway, Diego Cobice, David S. Gibson
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Journal of Personalized Medicine
Subjects:
rheumatoid arthritis
SNP
DMARD
methotrexate
pharmacogenomics
Online Access:https://www.mdpi.com/2075-4426/10/4/149

Internet

https://www.mdpi.com/2075-4426/10/4/149

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